Acetyltransferase enzymes play a crucial role in the regulation of gene expression by adding an acetyl group to histones.
乙酰转移酶在通过向组蛋白添加乙酰基来调节基因表达的过程中发挥关键作用。
The enzyme
acetyltransferase is responsible for catalyzing the transfer of an acetyl group from acetyl-CoA to a specific substrate.
乙酰转移酶负责催化将乙酰辅酶A中的乙酰基转移到特定底物上。
In drug metabolism, N-
acetyltransferase 2 (NAT2) is involved in the biotransformation and detoxification of various drugs and xenobiotics.
在药物代谢中,N-乙酰转移酶2(NAT2)参与各种药物和异生物质的生物转化和解毒过程。
Histone
acetyltransferases (HATs) are essential for modifying chromatin structure and influencing DNA transcriptional activity.
组蛋白乙酰转移酶(HATs)对于改变染色质结构和影响DNA转录活性至关重要。
Altered expression of cytosine
acetyltransferase may contribute to cancer development through epigenetic modifications.
胞嘧啶乙酰转移酶表达的改变可能通过表观遗传修饰方式促进癌症的发生发展。
The p300/CBP family of
acetyltransferases has been shown to be important for cellular growth, differentiation, and response to stress signals.
p300/CBP家族的乙酰转移酶已被证明在细胞生长、分化及对压力信号的响应中具有重要作用。
Non-nuclear
acetyltransferases, such as carnitine O-
acetyltransferase, function in metabolic pathways outside the nucleus.
非核内乙酰转移酶,如肉碱O-乙酰转移酶,在细胞核外的代谢途径中发挥作用。
Glutamine synthetase is subject to feedback inhibition by adenylyltransferase, which transfers an adenylyl group rather than an acetyl group.
谷氨酰胺合成酶受到腺苷酰转移酶(而非乙酰转移酶)的反馈抑制,该酶转移的是腺苷酰基团。
The overexpression of histone deacetylases can counteract the effects of
acetyltransferases in promoting gene transcription.
组蛋白去乙酰化酶的过度表达可以抵消乙酰转移酶在促进基因转录方面的作用。
Aminoacyl-tRNA synthetases often possess additional domains with editing functions or non-canonical activities, such as tyrosine aminoacyl-tRNA synthetase which also acts as a phenylalanine
acetyltransferase.
氨酰-tRNA合成酶通常具有额外的编辑功能域或非典型活性,例如酪氨酸氨酰-tRNA合成酶,它还作为苯丙氨酸乙酰转移酶发挥作用。
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