Bioactivation is the process by which inactive compounds, called prodrugs, are converted into their active forms in the body.
生物激活是指在体内将前药(prodrugs)转化为活性形式的过程。
The liver plays a crucial role in
bioactivation of many drugs through the action of cytochrome P450 enzymes.
肝脏通过细胞色素P450酶在生物激活许多药物过程中发挥关键作用。
Some environmental pollutants require
bioactivation before they can exert their toxic effects on cells.
有些环境污染物在对细胞产生毒性影响之前,需要经过生物激活。
A drug's bioavailability can be increased through
bioactivation, making it more effective in the body.
通过生物激活,药物的生物利用度可以提高,使其在体内的效果更显著。
The study found that certain individuals had a slower
bioactivation rate for a particular medication, affecting its efficacy.
研究发现,有些人对特定药物的生物激活速率较慢,这会影响其疗效。
Some drugs undergo
bioactivation in the intestines before being absorbed into the bloodstream.
有些药物在被吸收进入血液之前会在肠道内经历生物激活过程。
Bioactivation is an essential mechanism for detoxifying xenobiotics, which are foreign substances to our bodies.
生物激活是身体解毒外源性物质(如外来物质)的重要机制。
The effectiveness of chemotherapy drugs can be enhanced by
bioactivation, as it increases their ability to target cancer cells.
化疗药物的有效性可以通过生物激活增强,因为它提高了药物针对癌细胞的能力。
Researchers are investigating ways to manipulate
bioactivation pathways to develop safer and more targeted therapies.
研究人员正在探索如何调控生物激活途径,以开发更安全和更具针对性的疗法。
Environmental toxins often undergo
bioactivation to form reactive metabolites, which can cause cellular damage.
环境毒素通常经过生物激活形成反应性代谢产物,这些产物可能造成细胞损伤。
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