钙网蛋白

Calreticulin is a calcium-binding protein found in the endoplasmic reticulum of eukaryotic cells.
钙网蛋白是存在于真核细胞内质网中的钙结合蛋白。
It plays a crucial role in the formation and maintenance of protein folding machinery within the cell.
它在细胞内蛋白质折叠机制的形成和维持中起着关键作用。
Calreticulin is involved in the unfolded protein response (UPR) to help cells recover from stress.
钙网蛋白参与未折叠蛋白响应（UPR），帮助细胞从压力中恢复。
The gene encoding calreticulin is located on chromosome 16q24.1.
编码钙网蛋白的基因位于第16号染色体的q24.1区段。
Mutations in calreticulin have been associated with certain inherited diseases, such as dermatomyositis.
钙网蛋白的突变与某些遗传性疾病，如皮肤肌炎有关。
In cancer research, calreticulin expression can serve as a diagnostic marker for some malignancies.
在癌症研究中，钙网蛋白表达可作为某些恶性肿瘤的诊断标志。
Studies have shown that calreticulin can modulate immune cell function by interacting with toll-like receptors.
研究表明，钙网蛋白通过与 toll-like 受体相互作用，可以调节免疫细胞的功能。
Its presence on the cell surface can indicate cell stress or activation of the immune system.
细胞表面的钙网蛋白存在可能指示细胞压力或免疫系统的激活。
Calreticulin is also involved in the process of autophagy, where damaged proteins are degraded.
钙网蛋白还参与自噬过程，即降解受损蛋白质。
Researchers are exploring potential therapeutic applications of calreticulin-targeted therapies for various diseases.
研究人员正在探索针对钙网蛋白的疗法在多种疾病治疗中的潜在应用。