时间药理学

Chronopharmacokinetics studies the time-dependent changes in drug absorption, distribution, metabolism, and elimination.
时序药代动力学研究药物吸收、分布、代谢和消除随时间的变化。
Understanding chronopharmacokinetics is crucial for optimizing medication dosing regimens in patients with circadian rhythms.
理解时序药代动力学对于优化有昼夜节律患者的药物给药方案至关重要。
The peak plasma concentration of a drug can vary significantly depending on the chronopharmacokinetics of the individual.
药物的血浆峰浓度可能因个体的时序药代动力学而显著不同。
A chronopharmacokinetic analysis revealed that the antiplatelet effect of aspirin peaks in the morning.
时序药代动力学分析显示阿司匹林的抗血小板作用在早晨达到峰值。
To achieve therapeutic efficacy, chronopharmacokinetics must be taken into account when designing personalized treatment plans.
设计个性化治疗方案时，必须考虑时序药代动力学以实现治疗效果。
Monitoring chronopharmacokinetics can help predict and prevent drug interactions by adjusting dosages accordingly.
监测时序药代动力学有助于预测并防止药物相互作用，通过调整剂量来实现。
Chronopharmacokinetics plays a significant role in the development of sustained-release formulations to maintain therapeutic levels throughout the day.
时序药代动力学在长效制剂的研发中起着重要作用，以保持全天的治疗水平。
Clinicians need to consider chronopharmacokinetics when deciding on the most effective time to administer certain medications.
医生在决定何时给予某些药物时，需要考虑时序药代动力学。
By studying chronopharmacokinetics, researchers can better understand how a drug's effects vary across different times of the day.
通过研究时序药代动力学，研究人员能更深入地理解药物效果在一天中的变化。
Inadequate knowledge of chronopharmacokinetics can lead to suboptimal drug therapy and adverse drug events.
对时序药代动力学的了解不足可能导致药物治疗效果不佳及不良反应。