Cryptdin plays a crucial role in the immune response against gastrointestinal pathogens.
源自:Cryptdin在对抗胃肠道病原体的免疫反应中起到关键作用。
The expression of
cryptdin is induced by certain types of bacteria in the gut.
特定类型的肠道细菌可以诱导
cryptdin的表达。
Researchers have successfully cloned and sequenced the
cryptdin gene from mouse Paneth cells.
研究人员已成功从小鼠潘氏细胞中克隆并测序了
cryptdin基因。
Cryptdins are small antimicrobial peptides produced by Paneth cells in the small intestine.
Cryptdins是小肠潘氏细胞产生的小分子抗菌肽。
Studies show that
cryptdin exhibits potent bactericidal activity against both gram-positive and gram-negative bacteria.
研究表明,
cryptdin对革兰氏阳性和阴性细菌均显示出强大的杀菌活性。
Mice lacking
cryptdin production were found to be more susceptible to intestinal infections.
研究发现,不能产生
cryptdin的小鼠更容易感染肠道疾病。
A better understanding of
cryptdin function may lead to novel therapeutic strategies for treating inflammatory bowel diseases.
对
cryptdin功能有更深入的理解可能会为治疗炎症性肠病开辟新的治疗策略。
The regulation of
cryptdin synthesis is influenced by various factors, including hormones and cytokines.
cryptdin合成的调节受多种因素影响,包括激素和细胞因子。
Recent findings suggest that
cryptdin might also play a part in maintaining the balance of the gut microbiome.
最新发现表明,
cryptdin可能也在维持肠道微生物群落平衡方面发挥作用。
Current research is focusing on developing synthetic analogs of
cryptdin with improved stability and enhanced antimicrobial properties.
当前的研究正专注于开发具有改进稳定性和增强抗菌特性的
cryptdin合成类似物。
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