Cytosine is one of the four main nucleobases found in DNA and RNA.
胞嘧啶是DNA和RNA中发现的四种主要碱基之一。
The hydrogen bonding between guanine and
cytosine helps stabilize the structure of DNA.
鸟嘌呤和胞嘧啶之间的氢键有助于稳定DNA的结构。
During the process of transcription,
cytosine can pair with guanine on the opposite strand of DNA.
在转录过程中,胞嘧啶可以与DNA反向链上的鸟嘌呤配对。
In RNA,
cytosine often undergoes deamination to form uracil.
在RNA中,胞嘧啶通常会脱氨基形成尿嘧啶。
Methylation of
cytosine at CpG sites plays an important role in gene expression regulation.
在CpG位点胞嘧啶的甲基化在基因表达调控中起着重要作用。
A point mutation involving the substitution of adenine for
cytosine can lead to a frameshift mutation.
涉及将腺嘌呤替换为胞嘧啶的点突变可能导致阅读框移位突变。
The base excision repair mechanism recognizes and repairs damaged or incorrectly inserted
cytosine bases.
基本切除修复机制识别并修复受损或错误插入的胞嘧啶碱基。
In CRISPR-Cas9 technology,
cytosine bases within the protospacer adjacent motif (PAM) sequence are crucial for target recognition.
在CRISPR-Cas9技术中,原型spacer相邻基序(PAM)序列中的胞嘧啶碱基对于靶标识别至关重要。
Researchers have synthesized modified versions of
cytosine that can fluoresce under certain conditions, aiding in real-time DNA sequencing.
研究人员已经合成了在特定条件下能够发出荧光的胞嘧啶改良版本,从而有助于实时DNA测序。
Cytosine-arabinoside, also known as Ara-C, is an antineoplastic drug used in chemotherapy to treat some forms of leukemia.
胞嘧啶阿拉伯糖苷,也称为Ara-C,是一种用于化疗治疗某些形式白血病的抗肿瘤药物。
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