Exonucleases can degrade DNA by sequentially removing nucleotides from the ends of the molecule.
核酸外切酶可以通过依次从分子的末端移除核苷酸来降解DNA。
The action of
exonucleases is highly specific, targeting particular types of DNA damage for repair.
核酸外切酶的作用非常特异,针对特定类型的DNA损伤进行修复。
Exonucleases play a critical role in maintaining genome stability by preventing the accumulation of mutations.
核酸外切酶在维持基因组稳定性中起着关键作用,通过防止突变积累。
The activity of
exonucleases is regulated by various factors, including post-translational modifications and protein-protein interactions.
核酸外切酶的活性受到各种因素的调节,包括翻译后修饰和蛋白质-蛋白质相互作用。
The discovery of
exonucleases has led to the development of new techniques for DNA sequencing and analysis.
核酸外切酶的发现导致了DNA测序和分析新技术的发展。
Exonucleases can also be used in molecular biology research to generate DNA fragments of specific lengths.
核酸外切酶也可以用于分子生物学研究,以生成特定长度的DNA片段。
In some cases, mutations in
exonuclease genes can lead to genetic disorders or cancer.
在某些情况下,核酸外切酶基因的突变可能导致遗传性疾病或癌症。
The structure of
exonucleases has been extensively studied to understand their mechanism of action at the molecular level.
核酸外切酶的结构已被广泛研究,以了解其在分子水平上的作用机制。
Exonucleases are often found in conjunction with other DNA repair enzymes, forming complex repair pathways.
核酸外切酶通常与其他DNA修复酶一起被发现,形成复杂的修复途径。
The study of
exonucleases has important implications for understanding the evolution of DNA repair mechanisms.
对核酸外切酶的研究对于理解DNA修复机制的进化具有重要意义。
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