Fibrinogen is an essential clotting factor in the coagulation cascade, which is converted to fibrin during blood clot formation.
纤维蛋白原是凝血级联反应中的必需凝血因子,在血液凝固过程中转化为纤维蛋白。
The level of plasma
fibrinogen can be used as an indicator of inflammation and cardiovascular risk.
血浆纤维蛋白原水平可作为炎症和心血管风险的指标。
Fibrinogen is synthesized in the liver and plays a crucial role in hemostasis and wound healing.
纤维蛋白原在肝脏中合成,对止血和伤口愈合起着至关重要的作用。
A deficiency in
fibrinogen can lead to impaired blood clotting and increased bleeding tendency.
纤维蛋白原缺乏会导致血液凝固功能受损和出血倾向增加。
In patients with disseminated intravascular coagulation (DIC),
fibrinogen levels may drop significantly.
在弥散性血管内凝血(DIC)患者中,纤维蛋白原水平可能会显著下降。
Measurement of
fibrinogen degradation products can help diagnose and monitor diseases like deep vein thrombosis.
测定纤维蛋白原降解产物有助于诊断和监测深静脉血栓等疾病。
High levels of
fibrinogen are often associated with conditions such as obesity, diabetes, and coronary artery disease.
高水平的纤维蛋白原通常与肥胖、糖尿病和冠状动脉疾病等情况相关。
Fibrinogen can be transformed into insoluble fibrin by thrombin during the process of blood coagulation.
在血液凝固过程中,纤维蛋白原可通过凝血酶转化为不溶性的纤维蛋白。
During an acute phase response, the concentration of
fibrinogen in the blood typically increases due to its role as an acute-phase protein.
在急性期反应期间,由于纤维蛋白原作为急性期蛋白的作用,其在血液中的浓度通常会增加。
Treatment with anticoagulants might decrease
fibrinogen levels in order to prevent thrombotic events.
使用抗凝剂治疗可能降低纤维蛋白原水平,以防止血栓形成事件。
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