颗粒酶

Granzymes are proteolytic enzymes secreted by cytotoxic T cells, specifically targeting and destroying infected or abnormal cells.
The granzyme B release is a crucial step in the immune response to eliminate virus-infected cells.
Researchers found that granzymes can activate caspases, leading to programmed cell death.
Cytotoxic T lymphocytes armed with granzymes are essential for effective antiviral immunity.
In autoimmune diseases, granzymes contribute to the destruction of healthy cells by mistake.
Treatment strategies are being explored to modulate granzyme activity to prevent excessive tissue damage.
Granzymes play a pivotal role in the initiation of apoptosis in cancer cells during immunotherapy.
The balance between pro- and anti-granzyme factors is vital for maintaining immune homeostasis.
Excessive granzyme production can lead to tissue inflammation and tissue necrosis in chronic inflammatory conditions.
Scientists are working on developing targeted therapies that inhibit granzymes to treat severe inflammatory disorders.
干扰素是毒性T细胞分泌的蛋白水解酶，专门针对并破坏感染或异常细胞。
干扰素B的释放是免疫系统对病毒感染细胞消除的关键步骤。
研究人员发现干扰素能激活胱天蛋白酶，导致程序性细胞死亡。
拥有干扰素的杀伤性T淋巴细胞对于有效的抗病毒免疫至关重要。
在自身免疫疾病中，干扰素错误地破坏了健康细胞。
正在研究调节干扰素活性的方法，以防止过度的组织损伤。
干扰素在癌症免疫疗法中启动细胞凋亡过程中起着核心作用。
促进和抑制干扰素因素之间的平衡对于维持免疫稳态至关重要。
过量的干扰素产生会导致慢性炎症状况下的组织炎症和组织坏死。
科学家正在研发靶向疗法，抑制干扰素以治疗严重的炎症性疾病。