n.异染色质

Heterochromatin is typically transcriptionally inactive and late replicating.
异染色质通常转录不活跃且复制较晚。
The Barr body in female mammals represents the condensed heterochromatin of one X chromosome.
哺乳动物雌性体细胞中的巴氏小体代表一个高度浓缩的X染色体异染色质。
Heterochromatin plays an essential role in gene regulation, chromosome segregation, and genome stability.
异染色质在基因调控、染色体分离以及基因组稳定性方面发挥着至关重要的作用。
In Drosophila, position effect variegation is caused by the juxtaposition of euchromatin and constitutive heterochromatin.
在果蝇中，位置效应镶嵌是由 euchromatin（常染色质）与构成性异染色质相邻所导致的。
Histone modifications such as methylation are known to contribute to the formation and maintenance of heterochromatin.
已知组蛋白修饰如甲基化有助于异染色质的形成和维持。
Telomeres and centromeres are enriched for heterochromatin, which helps protect these chromosomal regions from degradation or recombination.
端粒和着丝粒富含异染色质，这有助于保护这些染色体区域免受降解或重组的影响。
Heterochromatin protein 1 (HP1) is a key factor involved in the assembly and spreading of heterochromatin domains.
异染色质蛋白1（HP1）是参与异染色质结构域组装和扩展的关键因子。
The presence of heterochromatin can silence nearby genes through a phenomenon known as position-effect silencing.
异染色质的存在可以通过位置效应沉默现象使附近的基因沉默。
During cellular differentiation, changes in heterochromatin organization contribute to cell type-specific gene expression patterns.
在细胞分化过程中，异染色质组织的变化有助于细胞类型特异性基因表达模式的形成。
Epigenetic studies have shown that dynamic changes in heterochromatin structure can influence the expression of developmentally regulated genes.
表观遗传学研究表明，异染色质结构的动态变化可以影响发育调控基因的表达。