Histones are proteins that package and organize DNA in eukaryotic cells, forming chromatin.
组蛋白是真核细胞中包裹和组织DNA的蛋白质,形成染色质。
The acetylation of
histones plays a crucial role in gene activation.
组蛋白的乙酰化在基因激活中起着关键作用。
Histones can undergo modifications such as methylation, which influences gene expression.
组蛋白可以发生甲基化等修饰,影响基因表达。
Histones H3 and H4 make up the core of chromatin, while others provide additional structure.
组蛋白H3和H4构成染色质的核心,而其他组蛋白提供额外的结构。
Epigenetic changes, including
histone modifications, are heritable but not DNA sequence.
表观遗传变化,如组蛋白修饰,是可遗传的但不随DNA序列改变。
During mitosis,
histones are compacted into chromosomes for cell division.
在有丝分裂期间,组蛋白被压缩成染色体以进行细胞分裂。
Histones help maintain genomic stability by regulating gene silencing.
组蛋白通过调控基因沉默来维持基因组稳定性。
In cancer, abnormal
histone levels often contribute to gene dysregulation.
在癌症中,异常的组蛋白水平常常导致基因调控失常。
Histones are subject to post-translational modifications by various enzymes.
组蛋白会受到各种酶的后翻译修饰。
Studies on
histones have shed light on the molecular mechanisms of gene expression.
对组蛋白的研究揭示了基因表达的分子机制。
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