The region of the promoter DNA showed
hypomethylation, indicating reduced gene expression.
启动子DNA区域出现甲基化程度降低,表明基因表达降低
Hypomethylation of repetitive elements is associated with genetic instability in cancer cells.
重复序列的低甲基化与癌细胞中的遗传不稳定有关
In utero
hypomethylation of specific genes has been linked to congenital disorders.
胎儿期特定基因的低甲基化与先天性缺陷有关
Epigenetic changes, including
hypomethylation, can silence transposable elements and prevent them from causing mutations.
包括低甲基化在内的表观遗传改变能沉默转座子,防止其引发突变
A study found that diet rich in antioxidants could reverse
hypomethylation in aging brains.
一项研究发现富含抗氧化剂的饮食可以逆转老年人大脑的低甲基化
Hypomethylation at CpG islands is often seen in response to stress, affecting gene expression.
在CpG岛的低甲基化常发生在应激情况下,影响基因表达
Genes involved in development show varying degrees of
hypomethylation during embryonic stages.
发育相关基因在胚胎阶段表现出不同程度的低甲基化
Chromatin remodeling through histone hypoacetylation/
hypomethylation is a key mechanism in cellular differentiation.
组蛋白去乙酰化/低甲基化是细胞分化的关键机制
In cancer, tumor suppressor genes often experience
hypomethylation, leading to their activation.
在癌症中,抑癌基因常经历低甲基化,从而被激活
Understanding
hypomethylation patterns in specific tissues can provide insights into disease development.
通过研究特定组织的低甲基化模式,可以揭示疾病发展的新线索
未经许可,严禁转发。QQ交流群:688169419