We gave no indication of how the work should be done.
我们没有给出任何关于这项工作该如何完成的指示。
This indication means that his dog will bite you.
这个迹象表明他的狗要咬人了
She gave no indication that she was ready to compromise.
她没有流露出打算妥协的迹象。
"In addition, obtaining high-quality endorsements from the FDA will also greatly assist in accelerating the approval of more indications of the product, especially in Southeast Asian countries where companies can accept applications for indications already listed in China," Li said.
李说：“此外，获得美国食品药品监督管理局的高质量背书也将大大有助于加快该产品更多适应症的审批，特别是在东南亚国家，这些国家的公司可以接受已经在中国上市的适应症申请。”。
Following the approval of a new indication, Toripalimab, China's first homegrown PD-1 anti-cancer treatment, has become the first approved perioperative therapy for lung cancer in China and the second worldwide, its developer Shanghai Junshi Biosciences Co Ltd said.
开发商上海君实生物科技有限公司表示，在新适应症获得批准后，中国首个国产PD-1抗癌治疗药物托里帕利单抗已成为中国首个获得批准的癌症围手术期治疗方法，也是全球第二个获得批准。
Launched in 2018, the flagship domestic cancer treatment has obtained seven indications.
2018年推出的旗舰国产癌症治疗已获得七个适应症。
The first six indications, including as a treatment for unresectable or metastatic melanoma after the failure of standard systemic therapy, have been included in the 2023 edition of the national reimbursement drug list.
前六个适应症，包括标准全身治疗失败后不可切除或转移性黑色素瘤的治疗，已被列入2023年版的国家报销药物清单。
The NMPA approval of the therapy, which is the first approved medicine with an IgAN indication in China, marks a new milestone in IgAN treatment in the country, said the company.
该公司表示，NMPA批准该疗法是中国首个批准的IgAN适应症药物，标志着中国IgAN治疗的一个新里程碑。
AbbVie plans to introduce over 30 new innovative drugs or indications into China by 2030, and foster the high-quality development of the country's healthcare industry through open and diverse collaboration, Lily Dong, Vice President and General Manager of AbbVie China, said in an interview.
AbbVie中国区副总裁兼总经理Lily Dong在接受采访时表示，AbbVie计划到2030年将30多种新的创新药物或适应症引入中国，并通过开放和多样化的合作促进中国医疗保健行业的高质量发展。
Benefiting from the spillover effect of CIIE, these two drugs will demonstrate the potential to treat more conditions of diseases, with the hope of getting approval on related indications in China soon.
得益于CIIE的溢出效应，这两种药物将显示出治疗更多疾病的潜力，有望很快在中国获得相关适应症的批准。
Dong emphasized that China's ongoing healthcare reform and the expedited new drug approval have benefited AbbVie, with Rinvoq as a particular example, which has been approved for seven indications within only 20 months after its launch in China.
董强调，中国正在进行的医疗改革和加快的新药审批使AbbVie受益，Rinvoq就是一个特别的例子，它在中国推出后仅20个月就获得了7个适应症的批准。
""It is now clear that the Chinese government aims to, and is giving every indication that it will, maintain the target GDP and set GDP per capita," he said.
他说：“现在很明显，中国政府的目标是保持目标国内生产总值，并设定人均国内生产总值。”。
Over the next five years, more than 15 new products and indications in animal health are expected to be approved in China, covering key species of commercial animals and companion animals, according to the company.
该公司表示，未来五年，预计中国将批准超过15种动物健康新产品和适应症，涵盖商业动物和伴侣动物的关键物种。
With a long-term commitment to the Chinese market, United States-based global pharmaceutical company MSD plans to introduce over 50 innovative drugs, vaccines, new indications and companion diagnostics to China in the next five years.
凭借对中国市场的长期承诺，总部位于美国的全球制药公司默沙东计划在未来五年内向中国引进50多种创新药物、疫苗、新适应症和配套诊断。
Since 2009, Bayer has introduced 19 innovative drugs with more than 30 new indications in China, data from the company showed.
拜耳公司的数据显示，自2009年以来，该公司已在中国推出19种创新药物，新适应症超过30种。
Global biopharmaceutical company GlaxoSmithKline is scheduled to submit market approvals in China for about 15 new drugs and indications over the next three years and more than 20 clinical research projects will be conducted in the country, said a senior executive of the company.
全球生物制药公司葛兰素史克的一位高管表示，该公司计划在未来三年内在中国提交约15种新药和适应症的市场批准，并将在中国开展20多个临床研究项目。
The quadrivalent flu vaccine Vaxigrip was approved in China in February for pediatric indications.
四价流感疫苗Vaxigrip于2月在中国获批用于儿科适应症。
He said the company is accelerating the expansion of its adult indications.
他说，该公司正在加快扩大其成人适应症。
XCMG's participation in the Las Vegas construction machinery trade show and the launch of the new Metaverse Ambassador NFT are clear indications of the company's ambition to become a global leader in the construction machinery industry and a pioneer in the metaverse world.
徐工参加拉斯维加斯工程机械贸易展和推出新的元宇宙大使NFT，清楚地表明了该公司成为工程机械行业全球领导者和元宇宙世界先驱的雄心。
In addition to traditional sports, such as football, badminton and swimming, emerging sports such as camping, flying disc, paddleboarding and skateboarding have also attracted more attention from a wider audience, an indication of the improving national economic level and people's pursuit of high-quality life, he said.
他说，除了足球、羽毛球和游泳等传统体育项目外，露营、飞碟、桨板和滑板等新兴体育项目也吸引了更多观众的关注，这表明国民经济水平的提高和人们对高品质生活的追求。
The company is pushing forward the therapy's approval for other new indications and the approval for another medicine to treat a rare neurofibroma, a neurological condition, to benefit more patients, said Hu.
胡说，该公司正在推进该疗法对其他新适应症的批准，以及对另一种治疗罕见神经纤维瘤（一种神经疾病）的药物的批准，以使更多患者受益。
These trials showed that the dosing interval was able to be extended to 16 weeks in two different indications with aflibercept 8xa0mg, compared with eight weeks for Eylea™, while maintaining a consistent safety profile.
这些试验表明，与Eylea的8周给药相比，在两种不同的适应症中，阿非利西普8xa0mg的给药间隔能够延长至16周™, 同时保持一致的安全状况。
US-based pharmaceutical company Bristol Myers Squibb has brought 12 innovations in the areas of oncology, hematology, and immunology to the ongoing 5th China international Import Expo and will continue to help patients with unmet needs in China by introducing up to 30 innovative medicines or indications by 2025, said its China president.
总部位于美国的百时美施贵宝制药公司中国总裁表示，该公司已将肿瘤学、血液学和免疫学领域的12项创新成果带到正在举行的第五届中国国际进口博览会上，并将在2025年前推出多达30种创新药物或适应症，继续帮助中国需求未得到满足的患者。
The company is planning to bring up to 30 innovative medicines or indications to China by 2025 and will be keenly involved in global early development programs to achieve simultaneous development in the areas of high unmet needs in China.
该公司计划到2025年将多达30种创新药物或适应症带到中国，并将积极参与全球早期开发计划，以实现在中国高需求未满足领域的同步开发。
More global research and innovation programs will be introduced into China on the basis that the company has around 150 pipeline projects in China, among which 90 percent are progressing neck to neck with relevant global programs, she said, adding that within the next five years, 60 to 65 new drugs or indications will be approved in China.
她说，在该公司在中国有大约150个管道项目的基础上，将有更多的全球研究和创新项目引入中国，其中90%的项目正在与相关的全球项目并驾齐驱。她补充说，在未来五年内，60至65种新药或适应症将在中国获批。
Regulatory filings are progressing in both prevention and treatment indications around the world.
监管文件在世界各地的预防和治疗适应症方面都取得了进展。
It is the sixth indication of Sintilimab being approved in China.
这是Sintilimab在中国获批的第六个适应症。
"Qatar Airways has demonstrated a robust role in the aviation industry, and these financial results are a clear indication of the group's strong performance," said Saad Bin Sharida Al-Kaabi, chairman of Qatar Airways.
卡塔尔航空公司董事长Saad Bin Sharida Al Kaabi表示：“卡塔尔航空公司在航空业发挥了强大的作用，这些财务业绩清楚地表明了该集团的强劲业绩。”。
"We currently have 150 research and development projects in China's R&D pipeline, and roughly 50 new drugs and new indications are expected to be approved in China in the next five years.
“我们目前有150个研发项目在中国研发，预计未来五年将有大约50种新药和新适应症在中国获批。
A sign of Sanofi's progress is that in 2021 it added 36 phase I and phase II clinical development programs, a clear indication of its strong pipeline of early-stage projects.
赛诺菲取得进展的一个迹象是，2021年，它增加了36个一期和二期临床开发项目，这清楚地表明了其早期项目的强大管道。
Zai Lab said it has also initiated Phase II confirmatory research for multiple new indications of the drug in China to accelerate the development of more autoimmune indications for the therapy on a global scale.
Zai Lab表示，它还在中国启动了该药物多种新适应症的II期验证研究，以加快在全球范围内开发更多的自身免疫适应症。
The implementation of the agreement between China and the European Union on the protection of geographical indications earlier this year, covering more than 270 European and Chinese agrifood names, would contribute to the world's economic recovery and support China's opening up, said Zhang Jianping, director-general of the China Center for Regional Economic Cooperation at the Chinese Academy of International Trade and Economic Cooperation in Beijing.
张建平说，今年早些时候中国和欧盟关于地理标志保护的协议的实施，涵盖了270多个欧洲和中国的农产品名称，将有助于世界经济复苏，支持中国的对外开放，北京中国国际贸易经济合作研究院中国区域经济合作中心主任。
A geographical indication is a sign used on products that have a specific geographical origin and possess qualities or a reputation due to that origin, the World Intellectual Property Organization said.
世界知识产权组织表示，地理标志是指用于具有特定地理来源并因该来源而具有质量或声誉的产品上的标志。
She said the company will actively carry out clinical trials to expand indications of the HPV vaccine in order to cover more age groups of the population.
她说，该公司将积极开展临床试验，扩大HPV疫苗的适应症，以覆盖更多年龄段的人群。
"Five innovative therapies and new indications in the digestion field are expected to be approved in the China market within five years," said Shan Guohong, senior vice-president of Takeda and president of Takeda China.
武田公司高级副总裁兼武田中国总裁单国洪表示：“消化领域的五种创新疗法和新适应症预计将在五年内在中国市场获得批准。”。
The agent's new indication for teenagers aged between 12 and 17 received market approval in China two months ago.
两个月前，该制剂针对12至17岁青少年的新适应症在中国获得了市场批准。
"The innovative injection's indication for children aged 6 or older has been included in the priority review by the national medical product authority.
“该创新注射剂针对6岁或6岁以上儿童的适应症已被纳入国家医疗产品管理局的优先审查。
US pharmaceutical giant Pfizer is aiming to launch 24 first-in-class new therapies and new indications and drugs in China market by 2025 as part of efforts to contribute to the Healthy China 2030 Initiative, the company's top executive for China said on Thursday, the first day of the 4th China International Import Expo (CIIE).
美国制药巨头辉瑞公司中国区首席执行官周四，即第四届中国国际进口博览会的第一天表示，作为为“健康中国2030”倡议做出贡献的努力的一部分，该公司计划到2025年在中国市场推出24种一流的新疗法、新适应症和药物。
In the case of MSD, its cancer immunotherapy has been approved through eight indications in China from its first approval in 2018, covering five tumor types.
Among them, the first approval in China for the melanoma indication took only five months from filing to approval, registering the fastest approval for an imported biologic in the country.
Dan Brindle, president of Novartis Group (China), said the company has had a strong flow of new drug approvals and therapies or indications included in the national reimbursement drug list to expand patients' accessibility to drugs over the past years.
"Brindle cited the example of Entrestro, a Novatis drug launched in China in 2017 to treat heart failure and approved for the new indication of essential hypertension in June.
"China was the world's second market to have the hypertension indication for this therapy.
Zeng Jianqiu, a professor of telecommunications economics at Beijing University of Posts and Telecommunications, said the move is an indication of China's commitment to further open its services sector and will bolster the development of the information communication industry over the long term.
That marked an important milestone for the vaccine in the therapeutic arena after it received the clinical trial nod for prevention indications in the UAE and New Zealand.
Chinese listed companies have registered a strong rebound in corporate earnings in the first half of the year, an indication that solid economic fundamentals will continue to attract global investors to the world's second-largest economy, leading experts said on Friday.
"During the process of gene sequencing, we acquire great amounts of genomic information, which doesn't specifically target one certain drug and satisfy pharmaceutical companies' various needs, such as the expansion of oncology drug indications, and the applicability for patients," he said.
Liu Xinwei, chief financial officer of OrigiMed, said: "We cooperate with drugmakers to collect genomic information needed in clinical research, design and optimize clinical experiments, develop testing products, quickly decide the drugs' new indication development direction, lower the R&D costs and accelerate the process of launching drugs.
Chinese smartphone maker Xiaomi Corp's removal from a United States Defense Department blacklist is further indication that the US government sanctions on Chinese companies are unwarranted, experts said.
"We view the announcement of the fine by the State Administration for Market Regulation on Saturday as an indication of the closure of the four-month antitrust investigation into Alibaba," said Alicia Yap, an analyst at Citigroup Global Markets Asia.
"Neither of these audits revealed any indications of the use of forced labor, either of Uygurs or any other ethnic or religious group, nor did the audits raise any other concerns about general labor conditions," the company wrote in its statement.
"Skechers also confirmed that, consistent with regular practice, it conducted multiple audits on Lu Zhou (the Dongguan supplier) in 2017, 2018, 2019 and 2020, both announced and unannounced, and that none of these audits revealed indications of the use of forced labor or other concerning labor conditions. "
United States-based Eli Lilly and Innovent, a domestic pharmaceutical company, jointly announced on Sunday the China market launch of a PD-1 inhibitor to be used for the indication of a main type of non-small cell lung cancer, a major tumor species threatening people's health in China and worldwide.
The drug, co-developed by Eli Lilly and Innovent, was actually approved by the National Medical Products Administration to treat classical Hodgkin's lymphoma as its first indication in December 2018, and was the first PD-1 inhibitor to be involved in the country's national reimbursement drug list.
This is an indication that China may emerge as the only major economy to have enjoyed positive growth last year in spite of the pandemic's adverse economic impacts across the globe.
A total of six new drugs and indications, including those for patients suffering from melanoma, ankylosing spondylitis (a rheumatic immune disease), and non-small cell carcinoma, were approved in China last year.
The company also said that in 2020, eight therapies or new indications were included in the NRDL to expand patients' accessibility to drugs and benefit more sufferers.
That marked the third approval in China for tislelizumab, and its first in a lung cancer indication.
"This is our sixth global approval for an internally developed product, and our first approval for tislelizumab in a lung cancer indication, an area where we believe tislelizumab can have a large impact for patients.
In Phase 3 trial in this indication, tislelizumab, combined with standard chemotherapy, demonstrated a clinically meaningful benefit as assessed by progression-free survival and response rates, Wang saidA total of 360 patients were randomized 1:1:1 to receive tislelizumab in combination with either chemotherapy regimen or chemotherapy alone during the trial.
This is an indication that it is likely to be the only major economy to enjoy positive growth in a year during which the pandemic emerged.
Jasmine Cui, co-founder, president and CEO of the company, said the launch of the drug set a milestone of the company development, and the enterprise will continue to accelerate clinical research and development of the drug for other indications and actively tap global market opportunities.
US biopharmaceutical company AbbVie said China is poised to become its largest overseas market outside of its headquarters, as it is on course to introduce 15 new drugs and 48 indications in the country over the next five years.
The injection, which has been approved by the United States Food and Drug Administration to treat moderate to severe AD among teenagers between 12 and 17 and minors between 6 and 11 in November last year and May respectively, will make its Asia debut with the indication for individuals in these age brackets.
Apple Inc's decision to limit iPhone purchases from its online stores in China is an indication of the supply chain constraints being faced by the US tech giant, as the novel coronavirus outbreak has disrupted normal operations at upstream suppliers and electronic component manufacturers, experts said.
"The commencement of construction is a clear indication of market demand despite the virus outbreak," said Wang Ziyue, analyst with China Wind Research at research firm BloombergNEF.
The anticipated disruption of the supply chain and reduced sales are key indications of possible impact of the outbreak on international businesses — even if the full effect isn't known.
"Holmes reserved her decision after the defense concluded its reply, with no indication how long it might be before she issues a ruling.
China is absolutely on top of the worldwide agenda of the company, which started its business in the country in 2012 and has two products for three indications so far, Wan said.
Novartis said that it has introduced innovative drugs into the China market at a faster pace – one to three new products or new indications – over the last three years, and at least 25 drugs treating tumors have been available in the country.
The Shanghai innovation hub, which was opened on Friday, together with an ensuing one in Guangzhou next month, is a clear indication of Merck's strong ties with the dynamic Chinese innovation ecosystem, said Stefan Oschmann, chairman and CEO of Merck Group.
"Boeing's earnings are an indication of how profitable the MAX has been and what a cash cow it's projected to be in the future,"Robert Mann, president of R. W. Mann & Co, an aviation consultancy, told China Daily.
However, staff from a Vodafone outlet in Madrid said that there were already many customers consulting them about 5G plans, an indication of great interest in the brand-new services.
According to a Financial Times report, Tencent is conducting trials with the relatively unknown UK digital health startup that are aimed at developing and validating algorithms that the companies hope will be able to predict complications across a range of disease indications, including Parkinson's, cancer, and heart disease.
Some villagers have been taking turns to offer food to the construction workers, he said, describing it as "an indication of the level of appreciation and happiness that they are enjoying now".
a clear indication of the market's liking for (our trade fair)," Pilotti told Xinhua.
In the second quarter of 2018, the Consumer Confidence Index - an indication of households' willingness to spend - climbed to 116 points in third-tier cities, from 112 in the previous quarter, according to Nielsen, a global data company.
Last month it was approved for asthma indication in the US.
Indications that the Changsha, Hunan province-based company was on the threshold of a huge success came after it said that its net profit for the first six months of this year was 3.389 billion yuan ($494 million), an increase of 192.09 percent over the same period a year ago.
“In general the cloud business will continue to grow but not at the previous pace and that’s an indication of the market maturity,” says Sid Nag, senior director, cloud technologies and services, Gartner Research.
"The establishment of the chip firm is a clear indication that Alibaba is extending its innovation capabilities to the manufacturing sector.
Haigh pointed out that these brands have experienced sky-rocketing revenues due to the boom in the Chinese market in recent years, but there are some indications that the boom is coming to an end.
Increased flights between Africa and China is an indication of growing trade and cultural exchanges between the two, with Nairobi emerging as the connecting hub for China and Africa, said Wu.
Though its prospectus to the Hong Kong Exchanges & Clearing Ltd on Thursday did not give any indication of the fundraising and valuation target, the Beijing-based company is reported to be seeking to raise about $10 billion, putting it on course to become the world's biggest IPO since Alibaba's $25 billion deal in 2014, and the largest in Hong Kong since AIA's $16.6 billion listing in 2010.
"The third quarter is an indication that those efforts are paying off as we successfully executed on delivering seasonal, relevant product from UGG with standout items, such as innovative winter and waterproof boots, slippers, the Classic Mini and the new men's styles," he said.
For a multinational company leader overlooking more than 60 markets, such a frequency is a strong indication of the company's focus on the Chinese market.
It is more of a strategic indication for us and it really enables us to continue the good work.
After receiving the earlier indications of interest, Murray Goulburn requested that firms submit formal bids by Oct 10, the people said.
An indication of the level of respect Disney accorded this unique Chinese exchange program is that the seminar speakers included such top-ranking creative and executive powerhouses as John Lasseter, Pixar co-founder and president of Walt Disney and Pixar Animation Studios, Ed Catmull, president of Walt Disney Animation Studios, Andrew Millstein, head of Production, Ann Le Cam, and Academy Award-winning producer, Roy Conli, as well as other top producers, writers and directors.
This is an indication that, after 10 years of operation, the nation's sovereign wealth fund is altering its investment strategy.
The move is seen as an indication of the strengthening influence that Didi is having on Ofo.
Sister app Alipay, which provides a wide variety of payments and other mobile services, also provides access to such business, a strong indication that Ant wants to enhance customer loyalty through its existing 450 million Alipay users, said Li Chao, a senior analyst at iResearch.
[Photo/VCG]Shanghai-based China Eastern Airlines has operated more than 270 flights between Shanghai and Prague since the route connecting the two cities opened, with the average occupancy rate being above 80 percent, an indication of the huge business potential in the Belt and Road Initiative.
We expected this project to be completed by December but indications on the ground are that we may do it earlier than December," Gwasira said.
"I do not want to go deep there as we will report annual results in May, but there are indications and quotes from industry experts, like from the CEO of Marriott Hotels Arne Sorenson, that the Middle East passenger demand for flights to the United States declined by double-digit rates," Antinori said.
As a vital component of expanding two-way financial market opening and an indication of China's growing global influence and overall strength, the promotion of RMB internationalization should be pushed ahead with diligence and prudence.
But should the conflict escalate in the Middle East, a heartland for world's oil production, substantial oil supply disruptions are likely, if historical trends are any indication.
In animal health, more than 15 new products and new indications will be approved in China in the next five years, covering key species of livestock and companion animals.
Winston Wu, spokesperson of Allergan Aesthetics China, said Allergan Aesthetics and its parent company AbbVie will join forces to participate in the CIIE for the third time and will display core brands in fields such as facial aesthetics, body contouring and functional skin care and more than 10 high-end products and multiple indications.
Italy, with its rich culinary heritage, envisages this expo as a golden opportunity to carve out new avenues for Italian gastronomy in the Chinese landscape, said Gianpaolo Bruno, trade commissioner of the Italian Trade Agency Beijing Office and coordinator of ITA Offices in China and Mongolia, during the Second Global Geographical Indications Products Expo held earlier week.
Being held in Luzhou, Sichuan province, the theme, of the expo was "Strengthen the Protection of Geographical Indications, Promote High-Quality Industrial Development".
This is another significant bilateral showcase and promotion event for geographical indications following the EU-China Geographical Indications Agreement reached in 2020.
Italy, being the EU's most accredited country in terms of geographical indication certifications, was a the choice.