培美曲塞

Pemetrexed is primarily used as an antifolate drug in the treatment of certain types of lung cancer.
翻译：培美曲塞主要用于作为抗叶酸药物治疗某些类型的肺癌。
The combination of pemetrexed and cisplatin has shown significant efficacy in patients with malignant pleural mesothelioma.
翻译：培美曲塞与顺铂联合使用在恶性胸膜间皮瘤患者中显示出了显著的疗效。
Pemetrexed is administered intravenously to inhibit the growth of tumor cells by interfering with their metabolic processes.
翻译：培美曲塞通过静脉注射给药，通过干扰肿瘤细胞的代谢过程来抑制其生长。
Patients receiving pemetrexed therapy should also take folic acid and vitamin B12 supplements to reduce side effects.
翻译：接受培美曲塞治疗的患者应同时服用叶酸和维生素B12补充剂以减少副作用。
Pemetrexed disodium is the active pharmaceutical ingredient in the brand name medication Alimta.
翻译：培美曲塞二钠是品牌药物Alimta中的活性药物成分。
Adverse reactions to pemetrexed may include fatigue, nausea, vomiting, and decreased appetite.
翻译：对培美曲塞的不良反应可能包括疲劳、恶心、呕吐以及食欲减退。
In clinical trials, pemetrexed demonstrated improved survival rates for patients with non-small cell lung cancer.
翻译：在临床试验中，培美曲塞证明了对非小细胞肺癌患者的生存率有所提高。
Treatment with pemetrexed should be initiated under the supervision of a medical oncologist.
翻译：使用培美曲塞的治疗应在肿瘤内科医生的监督下开始。
Regular blood tests are necessary during pemetrexed therapy to monitor potential hematologic toxicities.
翻译：在培美曲塞治疗期间需要定期进行血液检测以监测潜在的血液学毒性。
Pemetrexed can cause myelosuppression; therefore, careful monitoring of the patient's blood count is essential.
翻译：培美曲塞可能导致骨髓抑制；因此，密切关注患者的血细胞计数至关重要。