磷酸化

The enzyme phosphorylates the protein, thereby activating it.
酶使蛋白质磷酸化，从而激活它。
In signal transduction pathways, kinases often phosphorylate specific target proteins.
在信号传导途径中，激酶通常会磷酸化特定的目标蛋白。
Tyrosine residues on the insulin receptor are phosphorylated upon hormone binding.
胰岛素受体在激素结合后，其酪氨酸残基会被磷酸化。
Phosphorylation of AMPK by LKB1 is crucial for its activation in cellular energy homeostasis.
LKB1对AMPK的磷酸化对于其在细胞能量稳态中的激活至关重要。
Akt, a serine/threonine kinase, can phosphorylate and inactivate GSK-3β.
Akt是一种丝氨酸/苏氨酸激酶，可以磷酸化并使GSK-3β失活。
The process of phosphorylation often leads to a conformational change in the target molecule.
磷酸化过程常常导致目标分子构象的改变。
PKA (protein kinase A) can phosphorylate and regulate the activity of various substrates within the cell.
蛋白激酶A（PKA）可以磷酸化并调控细胞内多种底物的活性。
During mitosis, cyclin-dependent kinases phosphorylate numerous proteins involved in the cell cycle.
在有丝分裂过程中，周期素依赖性激酶会磷酸化参与细胞周期的众多蛋白质。
Calcium/calmodulin-dependent protein kinase II (CaMKII) phosphorylates itself and other proteins in response to calcium signaling.
钙/钙调蛋白依赖性蛋白激酶II（CaMKII）在钙离子信号响应下自我磷酸化和其他蛋白质。
The addition of phosphate groups through phosphorylation can either activate or deactivate enzymes and receptors, thus playing a critical role in cellular regulation.
通过磷酸化添加磷酸根团既可以激活也可以失活酶和受体，因此在细胞调控中发挥关键作用。