The activation of the protein kinase A (PKA) cascade leads to the
phosphorylation of several target enzymes.
蛋白激酶A(PKA)途径的激活会导致多个目标酶的磷酸化。
Akt, a key protein involved in cell survival, becomes phosphorylated upon insulin stimulation.
蛋白质Akt,参与细胞存活的关键因素,在胰岛素刺激下会被磷酸化。
Phosphorylation of the hormone-receptor complex is crucial for its function in signal transduction.
激素受体复合物的磷酸化对于信号转导至关重要。
Many signaling pathways, such as the MAPK pathway, involve sequential
phosphorylation events.
许多信号通路,如MAPK途径,包括一系列的磷酸化事件。
The de
phosphorylation of histone proteins by phosphatases marks the end of transcription.
去磷酸化的组蛋白由磷脂酶标记着转录的终止。
The tyrosine kinase receptor BCR-ABL undergoes auto
phosphorylation when it binds to its ligand.
当BCR-ABL酪氨酸激酶受体结合其配体时,会发生自磷酸化。
Protein kinases play a central role in regulating the process of
phosphorylation.
蛋白激酶在调控磷酸化过程方面起着核心作用。
The balance between
phosphorylation and de
phosphorylation determines cellular metabolism.
磷酸化和去磷酸化的平衡决定了细胞代谢。
The Ras protein's guanine nucleotide exchange factor (GEF) promotes its
phosphorylation and activation.
Ras蛋白的鸟苷酸交换因子(gef)促进其磷酸化和激活。
Epidermal growth factor receptor (EGFR)
phosphorylation can lead to cancer cell proliferation.
上皮生长因子受体(EGFR)的磷酸化可能导致癌细胞增殖。
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