蛋白酶体

The proteasome is a crucial component of the cellular machinery responsible for protein degradation.
蛋白酶体是负责蛋白质降解的细胞机器的重要组成部分。
In eukaryotes, ubiquitin-mediated degradation often targets proteins for destruction by the proteasome.
在真核生物中，泛素介导的降解常常将蛋白质定位给蛋白酶体进行破坏。
Researchers have discovered that certain drugs can inhibit the activity of the proteasome, leading to potential therapeutic applications.
研究人员发现某些药物能抑制蛋白酶体的活性，这为潜在的治疗应用提供了可能。
Proteasomes are found in all eukaryotic cells, playing a vital role in maintaining cellular homeostasis.
所有真核细胞中都存在蛋白酶体，它们在维持细胞稳态中起着关键作用。
After a protein has been tagged with ubiquitin, it's delivered to the proteasome for efficient degradation.
当蛋白质被泛素标记后，它会被送到蛋白酶体进行高效的降解。
Cancer cells often exhibit altered proteasome function, which can contribute to their uncontrolled growth.
癌细胞常常表现出蛋白酶体功能异常，这可能导致其不受控制的增长。
Proteasomes are involved in the destruction of misfolded proteins, preventing the accumulation of toxic aggregates.
蛋白酶体参与错误折叠蛋白质的降解，防止有毒性蛋白聚集。
Scientists have used CRISPR-Cas9 to modify the genes encoding proteasomes, offering insights into their role in various diseases.
科学家通过CRISPR-Cas9技术修改编码蛋白酶体的基因，从而揭示它们在各种疾病中的作用。
The proteasome's ability to degrade and recycle proteins allows cells to adapt and respond to changing conditions.
蛋白酶体能够降解和回收蛋白质，使细胞能够适应并应对不断变化的环境。
In the field of aging research, understanding the role of proteasomes in maintaining cellular health is a key focus.
在衰老研究领域，理解蛋白酶体在保持细胞健康中的作用是研究的重点。