巯基嘌呤

The patient was prescribed thiopurine to manage their autoimmune disorder.
翻译：病人被处方了硫嘌呤来管理他们的自身免疫疾病。
Thiopurines are commonly used as immunosuppressive agents in organ transplant recipients.
翻译：硫嘌呤类药物通常作为免疫抑制剂用于器官移植受者。
The efficacy of thiopurine therapy can be monitored by measuring thiopurine methyltransferase activity.
翻译：硫嘌呤疗法的效果可以通过测量硫嘌呤甲基转移酶活性来进行监测。
Adverse reactions to thiopurines may include nausea, vomiting, and liver enzyme abnormalities.
翻译：对硫嘌呤的不良反应可能包括恶心、呕吐和肝酶异常。
In the treatment of inflammatory bowel disease, thiopurines are often considered after initial 5-aminosalicylate therapy.
翻译：在治疗炎症性肠病时，常在初始使用5-氨基水杨酸治疗后考虑使用硫嘌呤类药物。
A genetic test is recommended before initiating thiopurine treatment due to potential hypersensitivity reactions.
翻译：由于潜在的超敏反应，建议在开始硫嘌呤治疗前进行基因检测。
The mechanism of action of thiopurines involves the disruption of DNA synthesis in rapidly dividing cells.
翻译：硫嘌呤的作用机制涉及破坏快速分裂细胞中的DNA合成。
Thiopurines, such as azathioprine and mercaptopurine, have been widely used in the treatment of leukemia.
翻译：像硫唑嘌呤和巯嘌呤这样的硫嘌呤类药物已被广泛用于白血病的治疗中。
Despite its therapeutic benefits, long-term use of thiopurine can increase the risk of infection and malignancy.
翻译：尽管硫嘌呤具有治疗益处，但长期使用会增加感染和恶性肿瘤的风险。
A dose adjustment of thiopurine may be necessary for patients with renal or hepatic impairment.
翻译：对于肾功能或肝功能受损的患者，可能需要调整硫嘌呤的剂量。