I'll need the
upfront payment before starting the project.
我需要在开始项目之前收到预付款。
The rent is due
upfront every month.
每个月的租金需要提前支付。
She asked for an
upfront commitment from her team.
她要求团队提前做出承诺。
The cost of the course is quite
upfront, but it includes all materials.
这门课程的费用很明确，包括所有教材。
We prefer to have
upfront discussions about any potential issues.
我们倾向于提前讨论可能出现的任何问题。
The job offer came with an
upfront salary negotiation.
工作机会伴随着提前的薪资谈判。
The
upfront investment in new technology will pay off in the long run.
对新技术的初期投资从长远来看会有回报。
The real estate agent requested an
upfront deposit for the property viewing.
房地产经纪人要求看房时支付押金。
The contract has an
upfront termination clause if either party breaches the agreement.
合同中有一个如果任何一方违约就可以提前终止的条款。
He was honest and
upfront about his past mistakes.
他对自己过去的错误坦诚不讳。
F-star will receive an undisclosed upfront payment and research funding during the collaboration and is entitled to potential development and commercialization milestone payments of up to $1 billion, plus potential annual net sales of any commercial products licensed amount of patent royalties.
F-star将在合作期间获得未披露的预付款和研究资金，并有权获得高达10亿美元的潜在开发和商业化里程碑付款，以及任何商业产品的潜在年度净销售额许可专利使用费。
Raymond Tam, chief financial officer of Adagene, said the company's gains from the authorization are fairly competitive in terms of both upfront fees and total potential milestone payments.
Adagene首席财务官Raymond Tam表示，该公司从授权中获得的收益在预付费和潜在里程碑付款总额方面都具有相当的竞争力。
Zhang Weilin, an analyst at Lead-Leo Research Institute, a market research provider, said: "Opening a coffee house requires relatively low upfront costs and it can generate high gross profits.
市场研究机构Lead Leo Research Institute的分析师张伟林表示：“开设咖啡馆需要相对较低的前期成本，而且可以产生较高的毛利润。
InnoCare will receive a $125 million upfront payment and is eligible to receive up to $812.5 million in potential development milestones and potential commercial payments should the collaboration achieve certain development, commercial milestones and sales thresholds.
InnoCare将获得1.25亿美元的预付款，并有资格根据合作研发达到一定里程碑、商业里程碑及销售门槛的情况下，额外获得高达8.125亿美元的潜在开发和商业付款。
Innovation, talent recruitment and retainment all key to worldwide successChinese startup Jacobio Pharmaceuticals, founded in 2015, recently received a $20 million milestone payment from global pharmaceutical giant AbbVie, marking the first milestone payment following the initial upfront fee of $45 million at the outset of Jacobio and AbbVie's collaboration inked in 2020.
创新、人才招聘和留任对于全球成功至关重要。成立于2015年的中国初创公司Jacobio Pharmaceuticals（加科思药业）最近收到了全球制药巨头艾伯维（AbbVie）支付的2000万美元里程碑付款，这是继2020年Jacobio和AbbVie合作之初支付的4500万美元预付款后，首次实现的里程碑付款。
In exchange for these commitments, Clover will receive a significant upfront payment, a payment upon positive Phase-2/3 data, and additional advance payments upon Gavi's exercise of options for doses to be delivered in 2022.
作为对这些承诺的回报，Clover将获得一大笔预付款，当取得积极的2/3期数据时将获得另一笔款项，如果Gavi行使在2022年交付疫苗剂量的期权，Clover还将获得额外的预付款。
AbbVie will pay I-Mab $180 million in an upfront payment, as well as $20 million in a milestone payment based on the Phase 1 results.
Hua Medicine will receive an upfront payment of 300 million yuan ($43.3 million) and additional payments could reach up to 4.18 billion yuan if certain milestones are met.
In announcing the partnership, the two companies said in a press release that the $200 million will help public and private sector clients accelerate the use of battery-powered electric buses by reducing upfront costs.
Wen, 36, is completely upfront about the reasons behind the relocation.
The report found that companies were bullish and expected the AI investment to be worth the upfront cost.
BeiGene will receive an aggregate of $413 million from Celgene in upfront licensing fees and equity investment, and will be eligible for up to an additional $980 million in development, regulatory, and sales milestones, as well as royalties on future sales of BGB-A317.
An obvious change that consumers may find at many of Watsons' refurbished or "G-next" (generation-next) stores is the new location of shelves for cosmetics－they have been moved from corners to upfront with more space, more lighting and more assortments.
BBD takes a percentage of profits rather than an upfront fee.
Allianz paid Standard Chartered about $200 million upfront to sell its general insurance products in Singapore, Malaysia, Indonesia and China.
"These wine and cosmetic products have a long shelf life and require smaller payments upfront, which has improved our cash flow to some extent.
Zhu Yi, a senior analyst at Bloomberg Intelligence, a market monitor, said implementing CCUS projects is currently expensive, as the technology requires a significant upfront investment.
With an enhanced safety performance and better upfront capital cost affordability, they offer options for remote regions with less developed infrastructures and the possibility to combine nuclear and alternate energy sources, including renewables, it said.
HBM shall receive an upfront payment of $25 million with the potential for additional payments up to $325 million pending the achievement of certain developments, and regulatory and commercial milestones.
The increase was partially offset by lower fees paid to external contract research organizations on clinical trials, as well as decreased expenses related to upfront fees for in-process R&D, the company said.
"Opening a milk tea store requires relatively low upfront costs and it can generate high gross profits.
开设一家奶茶店所需的初始投入成本相对较低，且能产生较高的毛利润。
Due to the abundant resources, the province can harness solar energy with smaller upfront investments and steady returns and this in turn helped in the poverty alleviation efforts, said Wei.
“由于资源丰富，该省可以在较小的前期投资和稳定的回报下利用太阳能，这反过来又有助于减贫工作，”魏说。
Cross-border e-commerce platforms must register with the authorities to conduct business activities in China, and bear the responsibility for upfront compensation," Feng said.
With comparatively smaller upfront investments and steady returns, solar-powered poverty relief makes for effective and sustainable programs that meet Qinghai's challenges in combating poverty, he said.
Chinese companies are shifting their focus from pure upfront costs to a more sustainable, life-cycle costs perspective, making them more willing to embrace highly efficient and environmentally reliable products, Dong said, adding that this offers good opportunities for Volvo.
As Chinese companies are shifting their focus from pure upfront costs to a more sustainable life-cycle-cost perspective, they become more willing to embrace highly efficient and environmentally reliable products, and this offers good opportunities for Volvo Group, he added.
Martin Lundstedt, president and CEO of Volvo Group, said Chinese companies are shifting their focus from pure upfront costs to a more sustainable life-cycle-cost perspective, which make them more willing to embrace highly efficient and environmentally reliable products, and this offers good opportunities for Volvo Group.
It has also extended its battery swapping program to ES6 owners, previously reducing the upfront price of the ES8 by 100,000 yuan.
Targeting a ninth consecutive record-breaking year, the group intends to increase upfront expenditure on R&D to an all-time high in 2018.
The major part of the investment will be pumped into upfront expenditure, primarily for the ongoing new models initiative, e-mobility and autonomous driving.
The first reason is mainly caused by alternative mobility solutions which have very competitive pricing (taxis or chauffeur-based vehicles with strong consumer incentives); the latter is mainly caused by car depreciation, upfront investment in offline solutions (maintenance team) and insurance.
BeiGene will receive an upfront cash payment of $650 million from Novartis and is eligible to receive up to $1.3 billion upon the achievement of regulatory milestones, and $250 million upon the achievement of sales milestones, in addition to royalties on future sales of tislelizumab in licensed territories.
"In the past, I used to feel a bit uneasy upon paying tuition fees upfront," Liu said.
Upon the request of the supplier, the Fuzhou-based joint-stock commercial lender later issued 50 million yuan to the supplier online via the letter of credit forfeiting service, which allows an exporter to receive upfront payment for selling letter of credit-based receivables at a discount on a non-recourse basis.
The company ended its reliance on outside brokers and instead began directly marketing its funds to investors without charging upfront fees known as sales loads.
Wan Xiaofang, president of Minsheng Financial Leasing, said: "Green environmental projects need huge upfront investment.
So far this year, more than 70 million people who required medical treatment outside their home provinces — and previously would have had to pay the full amount upfront — were able to pay only a portion of their expenses not covered by insurance.